Additional pediatric resources: GeneralPediatrics.com | PediatricEducation.org | SearchingPediatrics.com
A percutaneous biopsy was performed to exclude a malignant process. The biopsy findings were compatible with Histiocytosis X.
Histiocytosis X is caused by an abnormal proliferation of histiocytes. The classic finding on plain radiographs is flattening of the vertebral bodies known as "vertebra plana," and lytic lesions. Around the vertebral bodies, a soft tissue paravertebral mass may be seen. Although the diagnosis may often be made from plain film, a bone scan is often performed to look for distant lesions, as there may be multiple lesions in cases of Histiocytosis X. Once a lesion is discovered, CT and MRI may delineate it better, if necessary.
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