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Michael P. D'Alessandro, M.D.
Peer Review Status: Internally Peer Reviewed
Etiology/Pathophysiology:
Tranmission as autosomal dominant, but 50% of cases arise
spontaneously. The lesions start off being sessile and become
pedunculated over time. The polyps are adenomatous with malignant
potential and need treatment via a total colectomy as 95% of patients
who do not have a colectomy develop colon carcinoma by the 5th
decade. The most frequently involved site is the sigmoid.
Pathology:
Not applicable
Imaging Findings:
On an air contrast enema in older patients multiple polyps of
relatively uniform size and configuration are seen, ranging from 2-4
millimeters in diameter, that coat the colonic mucosa. In younger
patients you may only see serrations of the colonic mucosa that
resembles ulcerative colitis.
DDX:
References:
See References Chapter.
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