Additional pediatric resources: GeneralPediatrics.com | PediatricEducation.org | SearchingPediatrics.com
Michael P. D'Alessandro, M.D.
Peer Review Status: Internally Peer Reviewed
Etiology/Pathophysiology:
The skull has 3 embryonic divisions: (1) cerebral capsule (meninges,
calvarium, scalp), (2) face, and (3) floor of the skull. The cerebral
capsule and the face are formed directly from mesenchymal tissue via
intramembranous bone formation which is dependent on brain growth,
and their sutures close at variable times. The floor of the skull
develops via enchondral ossification which is not dependent on brain
growth, and its sutures close at a fixed time. By 8 years old brain
growth is 95% complete. Synchondrosis is the cartilaginous interface
between or within enchondral bones. The intersphenoid synchondrosis
disappears by 1 year while the the sphenooccipital synchondrosis
disappears in adolescence / early adulthood.
Pathology:
Not applicable
Imaging Findings:
Not applicable
DDX:
References:
See References Chapter.
Additional pediatric resources: GeneralPediatrics.com | PediatricEducation.org | SearchingPediatrics.com
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