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Michael P. D'Alessandro, M.D.
Peer Review Status: Internally Peer Reviewed
Clinical History:
The patient was an 11 year old male with a long-standing history of
plexiform neurofibromatosis involving his right arm and chest. His
past surgical history was remarkable for having multiple resections
of benign neurofibromas in the past.
Clinical Physical Exam:
Remarkable for an extensive soft tissue mass involving his right arm
and chest.
Clinical Labs:
Non-contributory
Clinical Differential Diagnosis:
Neurofibromatosis
Imaging Findings:
Spinal films and a chest CT exam demonstrated the extent of the right
thoracic mass and its bony involvement.
Imaging Differential Diagnosis:
Probably malignant degeneration of the plexiform neurofibroma due to
its rapid increase in size.
Operative Findings:
The patient underwent elective resection of the large right posterior
mediastinal mass. During the thoracotomy, the large mass was seen to
originate in the apex of the right chest.
Pathological Findings:
Examination of the surgical specimen revealed characteristic findings
of malignant schwannoma within a plexiform neurofibroma.
Final Diagnosis:
Neurofibroma of Thorax
Follow-up and Prognosis:
The patient had an uncomplicated post-operative course.
Similar Cases:
Case 15,
Case 18,
Case 27,
Case 46,
Case 67,
Case 69
References:
None
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